Our first paper of 2024 is out already!
In this paper we studied gene regulation in a very rare and poor survival AML with t(6;9) translocation and found that whilst on the surface level it looks like the common NPM1 driven AML, some key differences mean it may have to be treated differently to improve patient survival.
Read more here:
Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis – Leukemia
Leukemia – Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis